Scientific Literature - Related Materials and Abstracts

Holmes D R et al, Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomized non-inferiority trial, Lancet 2009;374:534-42.
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Sick P B et al, Initial Worldwide Experience with the WATCHMAN Left Atrial Appendage System for Stroke Prevention in Atrial Fibrillation. J Am Col Cardiol 2007;49:1490-5.
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Holmes DR, Schwartz R S, Left Atrial Appendage Occlusion Eliminates the Need for Warfarin. Circulation 2009;120:1919-1926.
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Wolf P.A., Abbott R.D., Kannel W.B. Atrial Fibrillation as an Independent Risk Factor for Stroke:  The Framingham Study.  Stroke 1991, 22(8):983-988.
http://stroke.ahajournals.org/cgi/reprint/22/8/983

Blackshear J.L., Odell J.A., Thoracoscopic Obliteration of the Appendage to Reduce Stroke in Cardiac Surgical Patients with Atrial Fibrillation.  Annals of Thoracic Surgery, 1996;61:755-759.
http://ats.ctsnetjournals.org/cgi/content/full/61/2/565

Garcia-Fernandez MA et al, Role of Left Atrial Appendage Obliteration in Stroke Reduction in Patients with Mitral Valve Prosthesis, A Transesophageal Echocardiographic Study. J Am Col Cardiol 2003;42:1253-1258.
http://content.onlinejacc.org/cgi/reprint/42/7/1253.pdf

Healey J.S., et al, Left Atrial Appendage Occlusion Study (LAAOS):  Results of a randomized controlled pilot study of left atrial appendage occlusion during coronary bypass surgery in patients at risk for stroke. Am Heart J 2005;150:288-93.
http://www.ahjonline.com/article/S0002-8703(05)00021-9/abstract

Sick P., Schuler G., et al., Left Atrial Appendage Filter Device for Prevention of Embolization in Patients with Non-Valvular Atrial Fibrillation:  Initial Results of a Multi-center Feasibility Trial. Presented at Transcatheter Cardiovascular Technologies, 2004.

Motei A., Holmes D.R., Packer D.L., Ravi B.S., Sinning P., Mookadam F., Khanderia B., Chandrasekaran K., Initial Experience with a Left Atrial Appendage Filter Device for Stroke Prevention in Atrial Fibrillation. Poster Presentation at American College of Cardiology, 2005.

Packer D., Krishnaswamy C., Peterson L., Monahan K., Holmes D.,  Utility of Intracardiac Ultrasound for Guiding Deployment of a Left Atrial Appendage Occlusion Devices for LAA Thrombus Prevention. Featured Poster Presentation at Heart Rhythm Society, 2005.

Daoud E., Holmes D., Mooney M., Packer D., Yakubov S., Turi Z.,  Early US Experience with Left Atrial Appendage Isolation. Poster Presentation at Heart Rhythm Society, 2005.

Sick P., Ulrich M., Schuler G., Hauptmann K.E., Grube E., Holmes D., Mishkel G., Yakubov S., Almany S., Turi Z., Mooney M., Stroke Prevention Technology for Patients with Non-Valvular AF - Worldwide Experience with the New WATCHMAN LAA System.  Poster Presentation at American College of Cardiology Annual Meeting, 2006.